Tridecapeptide-1
Synthetic 13-amino-acid peptide. The manufacturer claims stimulation of collagen and elastin synthesis, with rejuvenating and anti-ageing effects. Belongs to the 'signalling' peptide class. Independent clinical studies with efficacy comparable to retinol or vitamin C are not available. Positioned as a retinoid alternative for sensitive skin.
Evidence by route
Topical application
DVery weak or conflicting data.
Signalling peptides as a class show modest effects in a few controlled studies. Specific clinical data for Tridecapeptide-1 with adequate methodology are scarce. The primary evidence base is from the manufacturer; methodology is not in the open literature.
- Schagen SK. Cosmetics. 2017;4(2):16.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
Frequently asked questions
Is Tridecapeptide-1 safe during pregnancy?
Tridecapeptide-1 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Tridecapeptide-1 for?
Tridecapeptide-1 suits: normal, dry, combination, sensitive.