Neem Oil
INCI: Melia Azadirachta Seed Oil
Oil from seeds of the Indian neem tree (Azadirachta indica). Its characteristic garlic-sulphur odour is a major drawback. Used in Ayurveda and Indian cosmetics for acne, dandruff, psoriasis, and head lice. The main active is azadirachtin. Limited use outside India due to the smell; in the EU it is considered a moderate allergen.
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Antibacterial activity against Propionibacterium acnes and Staphylococcus aureus is confirmed in vitro. Clinical data for acne are limited to small Indian studies with weak methodology. Avoid in pregnancy due to data on potential azadirachtin embryotoxicity in experimental models.
- Sinha KK et al. J Ethnopharmacol. 2010;132(2):384-390.
Tolerability and safety
Irritation potential
MediumAllergen risk
ModeratePregnancy
AvoidSkin types
Suitable for
Use with caution
Frequently asked questions
Is Neem Oil safe during pregnancy?
Neem Oil is not recommended during pregnancy. Consider an alternative from the same category.
What skin types is Neem Oil for?
Neem Oil suits: oily, combination. Use with caution in: sensitive, dry.
Can Neem Oil irritate the skin?
Neem Oil has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.