Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate
Newest organic UV filter. Approved in the EU in 2022 and used in L'Oreal lines (La Roche-Posay Anthelios UVMUNE 400, Vichy Capital Soleil). Covers the longest-wavelength UVA range (UVA-I up to 400 nm), which most other filters do not reach. Used alongside Tinosorb S, Tinosorb M, and other modern filters.
Evidence by route
Topical application
AProven efficacy. Two or more independent RCTs with instrumental endpoints.
Clinical studies confirm significant reduction of photodamage in the long-wavelength UVA range (380-400 nm). This portion of the spectrum penetrates deep into the dermis and drives photoageing and pigmentation. Mexoryl 400 closes the gap left by prior filters.
- Sarkany RP et al. Photodermatol Photoimmunol Photomed. 2022;38(5):432-441.
- Passeron T et al. J Eur Acad Dermatol Venereol. 2024;38(Suppl 1):15-23.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
Frequently asked questions
Is Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate safe during pregnancy?
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate for?
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate suits: normal, dry, combination, oily, sensitive.