Ectoin
Small amino-acid-like osmolyte. Originally isolated from halophilic bacteria in salt lakes. In skin it binds water around cellular structures and membranes, protecting proteins and DNA against UV stress and dehydration. Used in formulations for sensitive and atopic skin and in post-laser protective creams.
Evidence by route
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Several controlled clinical studies confirmed moisturising and anti-inflammatory effects at 0.5-2% concentrations. In atopic skin studies, ectoin improved barrier function and reduced itch. The evidence base is modest but consistent.
- Heinrich U et al. Skin Pharmacol Physiol. 2007;20(4):211-218.
- Marini A et al. Skin Pharmacol Physiol. 2014;27(2):57-65.
- Buommino E et al. Curr Drug Targets. 2021;22(4):429-438.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
Frequently asked questions
Is Ectoin safe during pregnancy?
Ectoin is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Ectoin for?
Ectoin suits: normal, dry, combination, sensitive, oily.