Minor
Ascorbic acid × Cetirizine
Vitamins. Antioxidants×Second-generation antihistamines
Mechanism
Ascorbic acid does not affect cetirizine metabolism. The two are often combined in symptomatic preparations for acute respiratory infections.
Symptoms
The combination usually causes no specific symptoms. Each drug's individual side effects remain.
Management
No dose adjustment needed. The combination is standard in symptomatic formulations for acute respiratory infections and allergy.