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Safe feeding window

Simple one-compartment pharmacokinetic model: maternal plasma concentration halves every half-life. After 5 × T½ about 3% remains. The calculator shows when that window opens. Applies to a single dose of drugs without milk accumulation.

Prefilled from the drug card: Desloratadine

Sources

  • NIH LactMed – Drugs and Lactation Database
  • Hale TW. Medications and Mothers' Milk, Springer 2019, ch. 1.
  • Rowland M, Tozer TN. Clinical Pharmacokinetics and Pharmacodynamics, 4th ed. Lippincott 2011 (single-compartment model).